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Aflac Cancer and Blood Disorders Center of Children’s at Egleston

The Aflac Cancer Center is pediatric cancer center that provides advanced medical treatment, through clinical trials, and offers family-centered care and a child-friendly environment. Aflac Cancer Center physicians are involved in national clinical trials and collaborative studies of the Children’s Oncology Group (COG), the National Cancer Institute, the National Institutes of Health and the Pediatric Blood and Marrow Transplant Consortium. The Aflac Cancer Center is also a member of the Georgia CORE Research Network, a statewide network of academic and community-based oncologists and researchers. Children’s Healthcare of Atlanta is accredited by the American College of Radiology (ACR). Located in Atlanta, Georgia, the Aflac Cancer Center has three locations: Children’s at Egleston, Children's at Hughes Spalding and Children’s at Scottish Rite. Each location features the following services: full range of pediatric infusional and apheresis services; onsite, innovative diagnostics, cell processing laboratory and oncology pharmacy; a 20-plus-member family support team—including child life specialists, social workers, chaplains, teachers, psychologists and financial coordinators—that attends to the patient’s and family’s emotional, physical and financial well-being, as well as help the family identify and use all available resources during this difficult time.

Treatment Sites in Georgia

Clinical Trials in Georgia

A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL
Cancer Type: Leukemia

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Cancer Type: Hematopoietic Malignancies
Study Coordinator: Sindy Midoro


A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
Cancer Type: Leukemia

A Robot (My Special Aflac Duck) for the Reduction of Medical Setting Distress in Pediatric Cancer Patients
Cancer Type: Hematopoietic Malignancies, Solid Tumor

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors that Cannot be Removed by Surgery
Cancer Type: Unknown Primary

A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
Cancer Type: Neuroblastoma

A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
Cancer Type: Hodgkin Lymphoma

A Study of the Drugs Selumetinib versus Carboplatin/Vincristine in Patients with Neurofibromatosis and Low-Grade Glioma
Cancer Type: Brain & Spinal Cord Tumor

A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
Cancer Type: Leukemia, Non-Hodgkin Lymphoma

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Cancer Type: Leukemia, Neuroblastoma, Non-Hodgkin Lymphoma

A Study to Compare Treatments for a Type of Kidney Cancer called TFE/Translocation Renal Cell Carcinoma (tRCC)
Cancer Type: Kidney Cancer, Unknown Primary

A Study to Investigate Blinatumomab in Combination with Chemotherapy in Patients with Newly Diagnosed B-Lymphoblastic Leukemia
Cancer Type: Leukemia

Abemaciclib and Radiation Therapy in Treating Younger Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma, Recurrent or Refractory Solid Tumors, or Malignant Brain Tumors
Cancer Type: Brain & Spinal Cord Tumor, Neuroblastoma, Sarcoma

Accelerated or Standard BEP Chemotherapy in Treating Patients with Intermediate or Poor-Risk Metastatic Germ Cell Tumors
Cancer Type: Germ Cell Tumor, Testicular Cancer

Alisertib Alone or in Combination with Chemotherapy and Radiation Therapy in Treating Younger Patients with Recurrent, Progressive, or Newly Diagnosed Central Nervous System Atypical Teratoid Rhabdoid Tumors or Extra-Central Nervous System Malignant Rhabdoid Tumors
Cancer Type: Brain & Spinal Cord Tumor

An Open Label, Expanded Access Protocol Using 131I-metaiodobenzylguanidine (131I-MIBG)Therapy in Patients With Refractory Neuroblastoma, Pheochromocytoma, or Paraganglioma
Cancer Type: Adrenal Cancer, Neuroblastoma

AWAKE Mobile Application and Coaching Phone Calls in Improving Health-Promoting Behaviors in Adolescent Cancer Survivors and Their Guardians
Cancer Type: Hematopoietic Malignancies, Solid Tumor

Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
Cancer Type: Sarcoma

CD40 Agonistic Monoclonal Antibody APX005M in Treating Pediatric Patients with Recurrent or Refractory Brain Tumors
Cancer Type: Brain & Spinal Cord Tumor, Unknown Primary

Childhood Cancer Survivor Study
Cancer Type: Brain & Spinal Cord Tumor, Hodgkin Lymphoma, Leukemia, Lymphoma, Neuroblastoma, Non-Hodgkin Lymphoma, Solid Tumor
Study Coordinator: Sindy Midoro


Computer Training Program for Younger Patients with a Brain Tumor Who Underwent Radiation Therapy
Cancer Type: Brain & Spinal Cord Tumor, Unknown Primary

CX-4945 in Treating Patients with Recurrent SHH Medulloblastoma
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Unknown Primary

Ensartinib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Hematopoietic Malignancies, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Solid Tumor, Wilms Tumor

Erdafitinib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with FGFR Mutations (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Wilms Tumor

Everolimus, Nelarabine, Cyclophosphamide, and Etoposide Phosphate in Treating Patients with Relapsed or Refractory T Cell Lymphoblastic Leukemia or Lymphoma
Cancer Type: Hematopoietic Malignancies, Lymphoma, Non-Hodgkin Lymphoma, Unknown Primary

Health Effects After Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-Related Cardiomyopathy
Cancer Type: Hodgkin Lymphoma

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients with Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma
Cancer Type: Hodgkin Lymphoma

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells
Cancer Type: Bone Tumor, Neuroblastoma, Neurologocal Tumor

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab with or without Eflornithine in Treating Patients with Relapsed or Refractory Neuroblastoma
Cancer Type: Neuroblastoma

Larotrectinib in Treating Patients with Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia
Cancer Type: Brain & Spinal Cord Tumor, Solid Tumor

Larotrectinib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with NTRK Fusions (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Wilms Tumor

Matched Targeted Therapy Recommendation in Identifying Genetic Changes in Patients with Recurrent, Refractory, or High Risk Leukemia or Myelodysplastic Syndrome
Cancer Type: Leukemia, Myelodysplastic Syndromes (MDS)

MIBG With Dinutuximab +/- Vorinostat
Cancer Type: Neuroblastoma

Nab-Paclitaxel and Gemcitabine Hydrochloride in Treating Teenagers or Young Adults with Recurrent or Refractory Osteosarcoma, Ewing Sarcoma, Rhabdomyosarcoma, or Soft Tissue Sarcoma
Cancer Type: Sarcoma

Nab-paclitaxel followed by Gemcitabine Hydrochloride in Treating Pediatric Participants with Newly-Diagnostic, Relapsed or Refractory Solid Tumors
Cancer Type: Solid Tumor

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults with Blood Cancers Undergoing Donor Stem Cell Transplant
Cancer Type: Leukemia

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)
Cancer Type: Neuroblastoma

Neuroblastoma Biology Study
Cancer Type: Neuroblastoma

Nivolumab in Combination With 5-azacytidine in Childhood Relapsed/Refractory AML
Cancer Type: Leukemia

Olaparib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Wilms Tumor

Optune Delivered Electric Field Therapy in Treating Children with Recurrent, Progressive, or Refractory High-Grade Glioma or Supratentorial Ependymoma
Cancer Type: Brain & Spinal Cord Tumor

Palbociclib in Treating Patients with Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG
Cancer Type: Brain & Spinal Cord Tumor

Peginterferon alfa-2b in Treating Younger Patients with Recurrent or Refractory and Radiographically or Clinically Progressive Pilocytic Astrocytomas and Optic Pathway Gliomas
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Cancer-Related Syndrome, Unknown Primary

Pembrolizumab in Treating Younger Patients with Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
Cancer Type: Brain & Spinal Cord Tumor

Pilot Study of Neuropsychological and Behavioral Assessment in Children With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)
Cancer Type: Brain Tumor
Study Coordinator: Sindy Midoro


Research Study of Clinical, Genetic, and Biological Factors as Prognostic Values in Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Cancer Type: Neuroblastoma
Study Coordinator: Sindy Midoro


Rifaximin in Preventing Infections in Participants with Blood Cancer Undergoing Hematopoietic Stem Cell Transplantation
Cancer Type: Hematopoietic Malignancies

Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)
Cancer Type: Hodgkin Lymphoma

Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Cancer Type: Lymphoma, Neuroblastoma, Sarcoma

Selinexor in Treating Younger Patients with Recurrent or Refractory Solid Tumors or High-Grade Gliomas
Cancer Type: Brain & Spinal Cord Tumor, Lymphoma

Sirolimus and Metronomic Chemotherapy for the Treatment of High-Risk Solid Tumors in Children, AflacST1903 Study
Cancer Type: Sarcoma, Solid Tumor

Sirolimus and Metronomic Chemotherapy in Treating Younger Patients with Recurrent and/or Refractory Solid or Central Nervous System Tumors
Cancer Type: Solid Tumor

Standard Chemotherapy in Treating Young Patients with Medulloblastoma or Other Central Nervous System Embryonal Tumors
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Neuroblastoma, Neurologocal Tumor

Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients with Chronic Phase Chronic Myeloid Leukemia
Cancer Type: Leukemia

Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients
Cancer Type: Leukemia

Study of Key Late-Occurring Complications in Childhood Cancer Survivors
Cancer Type: Multiple Primaries
Study Coordinator: Sindy Midoro


Study of Long-Term Follow-Up in Patients Who Have Participated in Children's Oncology Group Studies
Cancer Type: Multiple Primaries
Study Coordinator: Sindy Midoro


Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors
Cancer Type: Neuroblastoma, Sarcoma

Study of Renal Tumors in Pediatric Patients
Cancer Type: Kidney Cancer
Study Coordinator: Sindy Midoro


Testing INCB007839 in Patients with Recurrent, Progressive High-Grade Glioma
Cancer Type: Brain & Spinal Cord Tumor

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders with HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
Cancer Type: Brain & Spinal Cord Tumor, Liver Cancer / Hepatoblastoma, Melanoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Thyroid Cancer

Trametinib in Treating Patients with Relapsed or Refractory Juvenile Myelomonocytic Leukemia
Cancer Type: Cancer-Related Syndrome, Hematopoietic Malignancies, Leukemia, Unknown Primary

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients with Newly Diagnosed Malignant Glioma without H3 K27M or BRAFV600 Mutations
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor

Vemurafenib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
Cancer Type: Brain & Spinal Cord Tumor, Brain Tumor, Germ Cell Tumor, Liver Cancer / Hepatoblastoma, Neuroblastoma, Non-Hodgkin Lymphoma, Sarcoma, Wilms Tumor

Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)
Cancer Type: Brain & Spinal Cord Tumor

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL
Cancer Type: Leukemia

WP1066 for the Treatment of Recurrent or Refractory and Progressive Malignant Brain Tumors
Cancer Type: Brain & Spinal Cord Tumor
**GeorgiaCancerInfo is not a medical practice. This is an informational web site provided by Georgia CORE, a nonprofit striving to provide current and comprehensive information on cancer care in Georgia through this website. If you find erroneous or missing information, please contact us.
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Advancing Cancer Care through Partnerships and Innovation

Georgia CORE is a statewide nonprofit that leverages partnerships and innovation to attract more clinical trials, increase research, and promote education and early detection to improve cancer care for Georgians in rural, urban, and suburban communities across the state.