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A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Ascending Doses of AZD5991 in Subjects With Relapsed or Refractory Haematologic Malignancies

Status
Active
Cancer Type
Hodgkin Lymphoma
Leukemia
Lymphoma
Multiple Myeloma
Myelodysplastic Syndromes (MDS)
Non-Hodgkin Lymphoma
Skin Cancer (Non-Melanoma)
Unknown Primary
Trial Phase
Phase I
Eligibility
18 to 85, Male and Female
Study Type
Treatment
NCT ID
NCT03218683
Protocol IDs
D6910C00001 (primary)
NCI-2017-01390
Study Sponsor
AstraZeneca Pharmaceuticals LP

Summary

This study is a multicenter, open-label, nonrandomized, sequential group, dose-escalation

study to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of

ascending doses of AZD5991 in subjects with relapsed or refractory hematologic malignancies.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University


1365 Clifton Road NE
Building C
Atlanta, GA 30322
404-778-5180
winshipcancer.emory.edu

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.
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