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A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of Ascending Doses of AZD5991 in Subjects With Relapsed or Refractory Haematologic Malignancies

Cancer Type
Hodgkin Lymphoma
Multiple Myeloma
Myelodysplastic Syndromes (MDS)
Non-Hodgkin Lymphoma
Skin Cancer (Non-Melanoma)
Unknown Primary
Trial Phase
Phase I
18 to 85, Male and Female
Study Type
Protocol IDs
D6910C00001 (primary)
Study Sponsor
AstraZeneca Pharmaceuticals LP


This study is a multicenter, open-label, nonrandomized, sequential group, dose-escalation

study to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of

ascending doses of AZD5991 in subjects with relapsed or refractory hematologic malignancies.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University

1365 Clifton Road NE
Building C
Atlanta, GA 30322

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.
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Georgia CORE is a public-private partnership that creates collaboration among the state’s cancer organizations and institutions to connect more Georgians to quality, personalized cancer care. We welcome you to this one-of-a-kind online information center for all things related to cancer and survivorship care in Georgia.