Summary
This Phase 2 study will be conducted in different countries around the world with up to
about 240 participants.
The purpose of this study is to evaluate how well Rina-S works against lung cancer.
The treatment in this study is Rina-S monotherapy (by itself). All participants will
receive active drug; no one will be given placebo.
The treatment duration will be different for every participant, but an average of 12
months is expected. Participants will be asked to attend 1 to 5 visits at the study
clinic for each cycle (duration of cycle is 3 weeks). If a participant's cancer stays the
same or gets better, and there are not any serious problems, participants can keep
getting study treatment for as long as the study is open.
Participation in the study will require visits to the study site(s). During site visits,
there will be various tests (such as blood draws) and procedures (such as recording of
heart activity, imaging/X-rays) to monitor whether the study treatment is safe and
effective.