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A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma


Active: No
Cancer Type: Kidney Cancer
Unknown Primary
NCT ID: NCT05805501
Trial Phases: Phase II Protocol IDs: BO43936 (primary)
NCI-2023-03569
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Hoffmann-La Roche
NCI Full Details: http://clinicaltrials.gov/show/NCT05805501

Summary

This study will evaluate the safety of tobemstomig (RO7247669) in combination with
axitinib alone or with tiragolumab (anti-TIGIT) and axitinib as compared to pembrolizumab
and axitinib in participants with previously untreated, unresectable locally advanced or
metastatic clear-cell renal cell carcinoma (ccRCC).

Treatment Sites in Georgia

Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
winshipcancer.emory.edu

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