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Dose-Escalation and Dose-Expansion Study of ZX-4081 in Patients With Advanced Solid Tumors

Active: Yes
Cancer Type: Breast Cancer
Colon/Rectal Cancer
Liver Cancer / Hepatoblastoma
Lung Cancer
Ovarian Cancer
Unknown Primary
NCT ID: NCT05118841
Trial Phases: Phase I Protocol IDs: ZX-4081 (primary)
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Nanjing Zenshine Pharmaceuticals
NCI Full Details:


A Phase 1, first-in-human, open-label, multicenter, dose escalation and dose expansion study
to investigate the safety, tolerability, PK, pharmacodynamics, and preliminary antitumor
activity of ZX-4081 administered orally (PO) twice daily (BID) in 28-day cycles in patients
with Advanced Solid Tumors.
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