Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer

Active:	Yes
Cancer Type:	Prostate Cancer	NCT ID:	NCT04848337
Trial Phases:	Phase II	Protocol IDs:	HCRN GU19-385 (primary) NCI-2021-06868
Eligibility:	18 Years and older, Male	Study Type:	Treatment
Study Sponsor:	University of Michigan Rogel Cancer Center
NCI Full Details:	http://clinicaltrials.gov/show/NCT04848337

Summary

Eligible patients will be treated with the combination of lenvatinib and pembrolizumab. A
cycle equals 21 days and therapy will continue until radiographic progression, intolerable
toxicity, or patient/physician wishes to discontinue protocol therapy. A maximum of 35 cycles
may be administered. On Day 1, when both pembrolizumab and lenvatinib are administered,
patients should take the lenvatinib per their normal routine.

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