Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Active:	No
Cancer Type:	Colon/Rectal Cancer Unknown Primary	NCT ID:	NCT04793958
Trial Phases:	Phase III	Protocol IDs:	849-010 (primary) NCI-2021-03009 KRYSTAL-10
Eligibility:	18 Years and older, Male and Female	Study Type:	Treatment
Study Sponsor:	Mirati Therapeutics
NCI Full Details:	http://clinicaltrials.gov/show/NCT04793958

Summary

Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of
MRTX849 administered in combination with cetuximab versus chemotherapy in the second-line
treatment setting in patients with CRC with KRAS G12C mutation.

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