Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

Active:	No
Cancer Type:	Colon/Rectal Cancer Esophogeal Cancer Stomach/ Gastric Cancer	NCT ID:	NCT03798626
Trial Phases:	Phase I	Protocol IDs:	CVPM087A2101 (primary) NCI-2019-04426 2018-003952-19
Eligibility:	18 Years and older, Male and Female	Study Type:	Treatment
Study Sponsor:	Novartis Pharmaceuticals Corporation
NCI Full Details:	http://clinicaltrials.gov/show/NCT03798626

Summary

This study will determine the pharmacodynamically-active dose of gevokizumab and the
tolerable dose of gevokizumab in combination with the standard of care anti-cancer therapy in
patients with metastatic colorectal cancer, metastatic gastroesophageal cancer and metastatic
renal cell carcinoma, and the preliminary efficacy of gevokizumab in combination with the SOC
anti-cancer therapy in subjects with mCRC and mGEC.

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