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A Study of Engineered Donor Grafts (TregGraft/Orca-T) in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Active: Yes
Cancer Type: Leukemia NCT ID: NCT04013685
Trial Phases: Phase I Protocol IDs: TRGFT-201 (primary)
Eligibility: 18 - 65 Years, Male and Female Study Type: Treatment
Study Sponsor: Orca Biosystems, Inc.
NCI Full Details:


This study will evaluate the safety, tolerability, and efficacy of an engineered donor graft
("TregGraft"/"Orca-T", a T-cell-Depleted Graft With Additional Infusion of Conventional T
Cells and Regulatory T Cells) in participants undergoing myeloablative allogeneic
hematopoietic cell transplant transplantation for hematologic malignancies.
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