Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Active:	Yes
Cancer Type:	Cancer-Related Syndrome Leukemia Myelodysplastic Syndromes (MDS)	NCT ID:	NCT04013685
Trial Phases:	Phase I	Protocol IDs:	TRGFT-201 (primary) NCI-2019-08529
Eligibility:	18 - 75 Years, Male and Female	Study Type:	Treatment
Study Sponsor:	Orca Biosystems, Inc.
NCI Full Details:	http://clinicaltrials.gov/show/NCT04013685

Summary

This study will evaluate the safety, tolerability, and efficacy of Orca-T, an allogeneic
stem cell and T-cell immunotherapy biologic manufactured for each patient (transplant
recipient) from the mobilized peripheral blood of a specific, unique donor. It is
composed of purified hematopoietic stem and progenitor cells (HSPCs), purified regulatory
T cells (Tregs), and conventional T cells (Tcons) in participants undergoing
myeloablative allogeneic hematopoietic cell transplant transplantation for hematologic
malignancies.

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