Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)

Active:	No
Cancer Type:	Hodgkin Lymphoma	NCT ID:	NCT03407144
Trial Phases:	Phase II	Protocol IDs:	3475-667 (primary) MK-3475-667 2017-001123-53 NCI-2018-00389
Eligibility:	3 - 25 Years, Male and Female	Study Type:	Treatment
Study Sponsor:	Merck Sharp & Dohme LLC
NCI Full Details:	http://clinicaltrials.gov/show/NCT03407144

Summary

This study will examine the safety and efficacy of pembrolizumab (MK-3475) in combination
with chemotherapy in children and young adults with newly diagnosed classical Hodgkin
Lymphoma (cHL) who are slow early responders (SERs) to frontline chemotherapy.

Objectives

Group 1 will consist of low-risk participants with cHL Stages IA, IB and IIA without bulky
disease. Group 2 will consist of high-risk participants with cHL Stages IIEB, IIIEA, IIIEB,
IIIB, IVA and IVB.

Treatment Sites in Georgia

Aflac Cancer and Blood Disorders Center of Children’s at Egleston
1405 Clifton Road NE
3rd Floor
Atlanta, GA 30322
404-785-0853
www.choa.org

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