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A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)


Active: No
Cancer Type: Lung Cancer
Solid Tumor
Unknown Primary
NCT ID: NCT03600883
Trial Phases: Phase I
Phase II
Protocol IDs: 20170543 (primary)
NCI-2018-01725
Eligibility: 18 - 100 Years, Male and Female Study Type: Treatment
Study Sponsor: Amgen, Inc.
NCI Full Details: http://clinicaltrials.gov/show/NCT03600883

Summary

Evaluate the safety and tolerability of sotorasib in adult subjects with KRAS p.G12C mutant
advanced solid tumors.

Estimate the maximum tolerated dose (MTD) and/or a recommended phase 2 dose (RP2D) in adult
subjects with KRAS p.G12C mutant advanced solid tumors.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
404-778-5180
winshipcancer.emory.edu

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