A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)

Active:	No
Cancer Type:	Head and Neck Cancer	NCT ID:	NCT03752398
Trial Phases:	Phase I	Protocol IDs:	XmAb23104-01 (primary) NCI-2019-00828 DUET-3
Eligibility:	18 Years and older, Male and Female	Study Type:	Treatment
Study Sponsor:	Xencor, Inc.
NCI Full Details:	http://clinicaltrials.gov/show/NCT03752398

Summary

This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and
regimen of XmAb23104, to describe safety and tolerability, to assess PK and
immunogenicity, and to preliminarily assess anti-tumor activity of XmAb23104 monotherapy
and combination therapy with ipilimumab in subjects with selected advanced solid tumors.

Treatment Sites in Georgia

Emory University Hospital - Atlanta
1364 Clifton Road NE
Atlanta, GA 30322
www.emoryhealthcare.org

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