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A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia


Active: No
Cancer Type: Leukemia NCT ID: NCT02723994
Trial Phases: Phase II Protocol IDs: INCB 18424-269 (primary)
NCI-2016-01687
AALL1521
Eligibility: 1 - 21 Years, Male and Female Study Type: Treatment
Study Sponsor: Incyte Corporation
NCI Full Details: http://clinicaltrials.gov/show/NCT02723994

Summary

This is a nonrandomized study of ruxolitinib in combination with a standard multi-agent
chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia. Part 1 of
the study will optimize the dose of study drug (ruxolitinib) in combination with the
chemotherapy regimen. Part 2 will evaluate the efficacy of combination chemotherapy and
ruxolitinib at the recommended dose determined in Part 1.

Treatment Sites in Georgia

Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta
Arthur M. Blank Hospital
2220 North Druid Hills Road NE
Atlanta, GA 30329
404-785-0853
www.choa.org

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.