Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

Active:	No
Cancer Type:	Breast Cancer	NCT ID:	NCT01506609
Trial Phases:	Phase II	Protocol IDs:	M12-895 (primary) 2011-002913-12
Eligibility:	18 Years and older, Male and Female	Study Type:	Treatment
Study Sponsor:	Abbvie
NCI Full Details:	http://clinicaltrials.gov/show/NCT01506609

Summary

The primary objective of the study is to assess the progression-free survival (PFS) of
oral veliparib in combination with TMZ or in combination with carboplatin and paclitaxel
compared to placebo plus carboplatin and paclitaxel in subjects with BRCA1 or BRCA2
mutation and locally recurrent or metastatic breast cancer.

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