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Perflutren Lipid Microspheres Ultrasound in Diagnosing Patients with Intraocular Tumors Undergoing Diagnostic Surgery

Active: Yes
Cancer Type: Eye Cancer
NCT ID: NCT01930968
Trial Phases: Protocol IDs: IRB0003943 (primary)
Eligibility: 20 Years and older, Male and Female Study Type: Diagnostic
Study Sponsor: Emory University Hospital/Winship Cancer Institute
NCI Full Details:


This clinical trial studies perflutren lipid microsphere ultrasound in diagnosing patients with intraocular (within the eye ball) tumors undergoing diagnostic surgery. Ultrasound is a procedure that uses high-energy sound waves to look at tissues and organs inside the body. Perflutren lipid microsphere is a contrast agent that helps doctors to see the blood vessels more clearly during ultrasound. Using perflutren lipid microsphere during intraocular ultrasound before eye surgery may help doctors see the blood vessels in and around the tumor and may help doctors determine whether the patient has melanoma or other intraocular tumors including retinal tumors.


I. To show that it is possible to acoustically identify microbubbles in vascular channels in intraocular tumors, including uveal melanoma, metastases and retinal tumors.

Patients undergo routine ocular ultrasonography and then receive perflutren lipid microsphere intravenously (IV) during the scheduled intraocular ultrasonography.

Treatment Sites in Georgia

Emory University Hospital - Atlanta
1364 Clifton Road NE
Atlanta, GA 30322

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