Lasers in Cancer Treatment
Laser therapy uses high-intensity light to treat cancer and other illnesses. Lasers
can be used to shrink or destroy tumors. Lasers are most commonly used to treat
superficial cancers (cancers on the surface of the body or the lining of internal
organs) such as basal cell skin cancer and the very early stages of some cancers,
such as cervical, penile, vaginal, vulvar, and non-small cell lung cancer.
Lasers also may be used to relieve certain symptoms of cancer, such as bleeding
or obstruction. For example, lasers can be used to shrink or destroy a tumor that
is blocking a patient’s trachea (windpipe) or esophagus. Lasers also can be used
to remove colon polyps or tumors that are blocking the colon or stomach.
Laser therapy can be used alone, but most often it is combined with other treatments,
such as surgery, chemotherapy, or radiation therapy. In addition, lasers can seal
nerve endings to reduce pain after surgery and seal lymph vessels to reduce swelling
and limit the spread of tumor cells.
Laser therapy is often given through a flexible endoscope (a thin, lighted tube
used to look at tissues inside the body). The endoscope is fitted with optical fibers
(thin fibers that transmit light). It is inserted through an opening in the body,
such as the mouth, nose, anus, or vagina. Laser light is then precisely aimed to
cut or destroy a tumor. Laser-induced interstitial thermotherapy (LITT) (or interstitial
laser photocoagulation) also uses lasers to treat some cancers. LITT is similar
to a cancer treatment called hyperthermia, which uses heat to shrink tumors by damaging
or killing cancer cells.
Three types of lasers are used to treat cancer: carbon dioxide (CO2) lasers,
argon lasers, and neodymium:yttrium-aluminum-garnet (Nd:YAG) lasers. Each of these
can shrink or destroy tumors and can be used with endoscopes. CO2 and argon lasers
can cut the skin’s surface without going into deeper layers. Thus, they can be used
to remove superficial cancers, such as skin cancer. In contrast, the Nd:YAG laser
is more commonly applied through an endoscope to treat internal organs, such as
the uterus, esophagus, and colon. Nd:YAG laser light can also travel through optical
fibers into specific areas of the body during LITT. Argon lasers are often used
to activate the drugs used in PDT.
The advantages of laser therapy are that Lasers are more precise than standard surgical
tools (scalpels), so they do less damage to normal tissues. As a result, patients
usually have less pain, bleeding, swelling, and scarring. With laser therapy, operations
are usually shorter. In fact, laser therapy can often be done on an outpatient basis.
It takes less time for patients to heal after laser surgery, and they are less likely
to get infections. Patients should consult with their health care provider about
whether laser therapy is appropriate for them. In clinical trials (research studies),
doctors are using lasers to treat cancers of the brain and prostate, among others.
Search for clinical trials in Georgia.
References in this section:
Adapted from the National Cancer Institute's PDQ Database: : http://www.cancer.gov/cancertopics/factsheet/Therapy/lasers.
(Accessed August 2013)