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Evaluation of the Impact of A Survivorship Care Plan and Embedded Navigation Tool (ASCENT) in Patients with Prostate Cancer Undergoing Curative-Intent Radiotherapy with Concurrent Androgen Deprivation Therapy (ADT)

Cancer Type
Prostate Cancer
Trial Phase
18 Years and older, Male
Study Type
Supportive care
Protocol IDs
Pro00088754 (primary)
Study Sponsor
Duke University Medical Center


This trial studies how well ASCENT works in participants with prostate cancer who are undergoing radiation treatment and ADT. This internet-based tool communicates prostate cancer management between participants and care providers which may help identify the effects of treatment on participants with prostate cancer.


I. Evaluate whether ASCENT enables patients to adhere to the survivorship guidelines with the use of the healthcare team as a whole.
II. Examine whether ASCENT improves coordination of care and the ability to address patient needs.

I. To measure general health status.
II. To evaluate for existence and severity of depression.
III. To determine prostate-cancer specific quality of life.
IV. To measure mental and physical functioning and overall health-related-quality of life.

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM I: Participants receive health care per institutional standard plus ASCENT via the True North (TrueNTH) website and access to a patient resource navigator (PRN). They also receive weekly engagement email and/or text reminders.

ARM II: Participants receive health care per institutional standard plus access to the public information on the TrueNTH website; such as the symptom tracker, exercise & diet, and lived experiences modules.

Participants are followed up at 2, 4, and 6 months.
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