Data and Specimen Registry of Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
0 to 21 years, Male and Female
Collecting and storing samples of tissue(TISH-oo)
A group or layer of cells that work together to perform a specific function. from patients with cancer(KAN-ser)
A term for
diseases in which abnormal cells divide without control and
can invade nearby tissues. Cancer cells can also spread to
other parts of the body through the blood and lymph
systems. There are several main types of cancer. Carcinoma
is a cancer that begins in the skin or in tissues that line
or cover internal organs. Sarcoma is a cancer that begins in
bone, cartilage, fat, muscle, blood vessels, or other
connective or supportive tissue. Leukemia is a cancer that
starts in blood-forming tissue such as the bone marrow, and
causes large numbers of abnormal blood cells to be produced
and enter the blood. Lymphoma and multiple myeloma are
cancers that begin in the cells of the immune system.
Central nervous system cancers are cancers that begin in
the tissues of the brain and spinal cord. Also called malignancy. to test in the laboratory may help the study of cancer in the future.
This research study(reh-SERCH STUH-dee)
A scientific study of nature that sometimes includes processes involved in health and disease. For example, clinical trials are research studies that involve people. These studies may be related to new ways to screen, prevent, diagnose, and treat disease. They may also study certain outcomes and certain groups of people by looking at data collected in the past or future. is collecting and storing tissue samples from patients with rare or cutaneous(kyoo-TAY-nee-us)
Having to do with the skin.non-Hodgkin lymphoma(non-HOJ-kin lim-FOH-muh)
Any of a large group of cancers of lymphocytes (white blood cells). Non-Hodgkin lymphomas can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of non-Hodgkin lymphoma. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell non-Hodgkin lymphomas include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell non-Hodgkin lymphomas include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell non-Hodgkin lymphomas. Prognosis and treatment depend on the stage and type of disease. Also called NHL..
- To determine the clinical features, treatment, and outcome of patients with rare or cutaneous pediatric non-Hodgkin lymphoma (NHL).
- To determine the pathologic and biologic features of these diseases, including molecular diagnostics
and flow cytometry.
- To establish a bank of these pathologically reviewed diseases and make specimens of blood and tissue
available to qualified researchers.
- To determine sub-groups of these diseases that could be targeted for future biologic, pathologic, or therapeutic
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