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A Phase 2, Prospective, Randomized, Open-Label Study on the Efficacy of Defibrotide Added to Standard of Care Immunoprophylaxis for the Prevention of Acute Graft-versus-Host-Disease in Adult and Pediatric Patients After Allogeneic Hematopietic Stem Cell Transplant

Status
Active
Cancer Type
Bone and Soft Tissue (including Sarcoma)
Myelodysplastic Syndromes (MDS)
Trial Phase
Phase II
Eligibility
1 - 74 Years, Male and Female
Study Type
Treatment
NCD ID
NCT03339297
Protocol IDs
JZP963-201 (primary)
NCI-2018-00520
Study Sponsor
Jazz Pharmaceuticals

Summary

This is a study comparing the defibrotide prophylaxis arm vs standard of care arm for the prevention of aGvHD.
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