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A Phase I, Open-label, Multiple-ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of MSB0010718C in Subjects With Metastatic or Locally Advanced Solid Tumors and Expansion to Selected Indications

Status
Active
Cancer Type
Bladder Cancer
Trial Phase
Phase I
Eligibility
18 and older, Male and Female
Study Type
Treatment
NCD ID
NCT01772004
Protocol IDs
EMR 100070-001 (primary)
2013-002834-19
Study Sponsor
EMD Serono
NCI Full Details

Summary

This is a Phase 1, open-label, dose-escalation trial of MSB0010718C [antibody targeting programmed death ligand 1 (anti PD-L1)] with consecutive parallel group expansion in subjects with selected tumor indications.
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