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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis


Active: Yes
Cancer Type: Cancer-Related Syndrome
Leukemia
Myelodysplastic Syndromes (MDS)
NCT ID: NCT04996875
Trial Phases: Phase II Protocol IDs: CGT9486-20-201 (primary)
2021-001010-10
NCI-2021-09477
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Cogent Biosciences, Inc.
NCI Full Details: http://clinicaltrials.gov/show/NCT04996875

Summary

This is an open-label, two-part Phase 2 study investigating CGT9486 for the treatment of
patients with Advanced Systemic Mastocytosis (AdvSM), including patients with Aggressive
SM (ASM), SM with Associated Hematologic Neoplasm (SM-AHN), and Mast Cell Leukemia (MCL).
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